Citation: Xiao Hua XU, Jing Yu SU. A New Cytotoxic Dihydroxy Sterol from Laurencia Majuscula[J]. Chinese Chemical Letters, ;1997, 8(3): 235-236. shu

A New Cytotoxic Dihydroxy Sterol from Laurencia Majuscula

Xiao Hua XU ^a,b ,
Jing Yu SU ^a,b

a The Key National Laboratory of Elemento-Organic Chemistry, Tianjin 300071;
b Department of Chemistry, Zhongshan University, Guangzhou 510275

Received Date: 17 December 1996

24s-Stigmasta,4,25-diene,3β,6β-diol 1,a new sterol has been isolated from the algae Laurencia majuscula collected from the south China sea.Its structure was elucidated by spectroscopic methods.Compound 1 was cytotoxic against the P-388 cell line with an IC₅₀ value of 1.2 μg/ml.
1. [1]
  Muhammad Nafees , Muhammad Hanif , Piaoping Yang . Metallodrugs: From mere cytotoxic agents to immune modulators and checkpoint inhibitors. Chinese Chemical Letters, 2026, 37(4): 111013-. doi: 10.1016/j.cclet.2025.111013
2. [2]
  Yun-Feng Liu , Hui-Fang Du , Ya-Hui Zhang , Zhi-Qin Liu , Xiao-Qian Qi , Du-Qiang Luo , Fei Cao . Chaeglobol A, an unusual octocyclic sterol with antifungal activity from the marine-derived fungus Chaetomium globosum HBU-45. Chinese Chemical Letters, 2025, 36(3): 109858-. doi: 10.1016/j.cclet.2024.109858
3. [3]
  Guo-Ping Yin , Ya-Juan Li , Li Zhang , Ling-Gao Zeng , Xue-Mei Liu , Chang-Hua Hu . Citrinsorbicillin A, a novel homotrimeric sorbicillinoid isolated by LC-MS-guided with cytotoxic activity from the fungus Trichoderma citrinoviride HT-9. Chinese Chemical Letters, 2024, 35(8): 109035-. doi: 10.1016/j.cclet.2023.109035
4. [4]
  Bo Yang , Suqiong Yan , Shirong Ban , Wei Huang . New horizons in phosphorus-based emitters: From circularly polarized fluorescence to room-temperature phosphorescence. Chinese Chemical Letters, 2025, 36(11): 110837-. doi: 10.1016/j.cclet.2025.110837
5. [5]
  Hong-Jin Liao , Zhu Zhuo , Qing Li , Yoshihito Shiota , Jonathan P. Hill , Katsuhiko Ariga , Zi-Xiu Lu , Lu-Yao Liu , Zi-Ang Nan , Wei Wang , You-Gui Huang . A new class of crystalline X-ray induced photochromic materials assembled from anion-directed folding of a flexible cation. Chinese Chemical Letters, 2024, 35(8): 109052-. doi: 10.1016/j.cclet.2023.109052
6. [6]
  Hongshan Wang , Zhenglong Li , Ran An , Zhenyou Wang , Juanjuan Lu , Guansong Zheng , Zhihua Yang , Yu Chu , Junjie Li . NaAg3Ga8S14: A new diamond-like framework infrared nonlinear optical material derived from AgGaS2. Chinese Journal of Structural Chemistry, 2025, 44(12): 100757-100757. doi: 10.1016/j.cjsc.2025.100757
7. [7]
  Weizhong LING , Jingyi LIN , Jianglin ZHU , Yuyi LIANG , Shanshan DAI , Yu LI . Syntheses, structures, and catalytic performances of complexes with 4,4′-dihydroxy-[1,1′-biphenyl]-3,3′-dicarboxylic acid ligands. Chinese Journal of Inorganic Chemistry, 2026, 42(1): 152-160. doi: 10.11862/CJIC.20250204
8. [8]
  Feibin Wei , Yongfang Rao , Yu Huang , Wei Wang , Hui Mei . The new challenges for the development of NH₃-SCR catalysts under new situation of energy transition in power generation industry. Chinese Chemical Letters, 2024, 35(6): 108931-. doi: 10.1016/j.cclet.2023.108931
9. [9]
  Xu-Hui Yue , Xiang-Wen Zhang , Hui-Min He , Lei Qiao , Zhong-Ming Sun . Synthesis, chemical bonding and reactivity of new medium-sized polyarsenides. Chinese Chemical Letters, 2024, 35(7): 108907-. doi: 10.1016/j.cclet.2023.108907
10. [10]
  Qinming Wu , Xiangju Meng . New zeolites with extra-stable extra-large-pore. Chinese Journal of Structural Chemistry, 2024, 43(6): 100310-100310. doi: 10.1016/j.cjsc.2024.100310
11. [11]
  Keyang Li , Yanan Wang , Yatao Xu , Guohua Shi , Sixian Wei , Xue Zhang , Baomei Zhang , Qiang Jia , Huanhua Xu , Liangmin Yu , Jun Wu , Zhiyu He . Flash nanocomplexation (FNC): A new microvolume mixing method for nanomedicine formulation. Chinese Chemical Letters, 2024, 35(10): 109511-. doi: 10.1016/j.cclet.2024.109511
12. [12]
  Yin-Hang Chai , Li-Long Dang . New structural breakthrough and topological transformation of homogeneous metalla[4]catenane compounds. Chinese Journal of Structural Chemistry, 2024, 43(10): 100322-100322. doi: 10.1016/j.cjsc.2024.100322
13. [13]
  Yingjie Wang , Peng Tang , Wenchao Tu , Qi Gao , Cuizhu Wang , Luying Tan , Lixin Zhao , Hongye Han , Liefeng Ma , Kouharu Otsuki , Weilie Xiao , Wenli Wang , Jinping Liu , Yong Li , Zhajun Zhan , Wei Li , Xianli Zhou , Ning Li . Highly anticipated natural diterpenoids as an important source of new drugs in 2013–2023. Chinese Chemical Letters, 2025, 36(1): 109955-. doi: 10.1016/j.cclet.2024.109955
14. [14]
  Yunlong Sun , Wei Ding , Yanhao Wang , Zhening Zhang , Ruyun Wang , Yinghui Guo , Zhiyuan Gao , Haiyan Du , Dong Ma . New insight into manganese-enhanced abiotic degradation of microplastics: Processes and mechanisms. Chinese Chemical Letters, 2025, 36(3): 109941-. doi: 10.1016/j.cclet.2024.109941
15. [15]
  Qijie Gong , Jian Song , Yihui Song , Kai Tang , Panpan Yang , Xiao Wang , Min Zhao , Liang Ouyang , Li Rao , Bin Yu , Peng Zhan , Saiyang Zhang , Xiaojin Zhang . New techniques and strategies in drug discovery (2020–2024 update). Chinese Chemical Letters, 2025, 36(3): 110456-. doi: 10.1016/j.cclet.2024.110456
16. [16]
  Jing Guo . New electrolyte concept: Compact ion-pair aggregate electrolyte. Chinese Chemical Letters, 2025, 36(4): 110512-. doi: 10.1016/j.cclet.2024.110512
17. [17]
  Shengtao Jiang , Mengjiao Xie , Limin Jin , Yifan Ren , Wentian Zheng , Siping Ji , Yanbiao Liu . New insights into electrocatalytic singlet oxygen generation for effective and selective water decontamination. Chinese Chemical Letters, 2025, 36(5): 110293-. doi: 10.1016/j.cclet.2024.110293
18. [18]
  Yue Pan , Jing Ren , Yifan Sun , Luying Lu , Jia Gao , Liping Chen , Shancheng Yan , Zhiyang Li . Harnessing chirality: A new dawn in inorganic nanomaterial synthesis and biomedical applications. Chinese Chemical Letters, 2026, 37(4): 110791-. doi: 10.1016/j.cclet.2024.110791
19. [19]
  Ruizhi Yang , Xia Li , Weiping Guo , Zixuan Chen , Hongwei Ming , Zhong-Zhen Luo , Zhigang Zou . New thermoelectric semiconductors Pb5Sb12+xBi6-xSe32 with ultralow thermal conductivity. Chinese Journal of Structural Chemistry, 2024, 43(3): 100268-100268. doi: 10.1016/j.cjsc.2024.100268
20. [20]
  Chao Ma , Peng Guo , Zhongmin Liu . DNL-16: A new zeolitic layered silicate unraveled by three-dimensional electron diffraction. Chinese Journal of Structural Chemistry, 2024, 43(4): 100235-100235. doi: 10.1016/j.cjsc.2024.100235

Get Citation

PDF

XML

Metrics

PDF Downloads(6)
Abstract views(1317)
HTML views(20)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Address：Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888

DownLoad: Full-Size Img PowerPoint

Return