Citation: Hui LIU, Lin XIA, Yun Hua YE. Organophosphorus Compound DEPBT as a Coupling Reagent for Oligopeptides and Peptoids Synthesis:Studies on Its Mechanism[J]. Chinese Chemical Letters, ;2002, 13(7): 601-604. shu

Organophosphorus Compound DEPBT as a Coupling Reagent for Oligopeptides and Peptoids Synthesis:Studies on Its Mechanism

Hui LIU ^1, ,
Lin XIA ¹ ,
Yun Hua YE ²

1.
Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009;
2.
College of Chemistry and Molecular Engineering, Peking University, Beijing 100871

Received Date: 22 October 2001

Some oligopeptidcs and peptoids were synthesized by applying the organophosphorus compound DEPBT as a coupling rcagent. D-Biotin-OOBt was obtained unexpcctcdly. A proposed reaction mechanism for DEPBT-mediated coupling was proved.
- Amino acids,
- peptides,
- phosphorus,
- coupling
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