Citation: Yun TANG, Kai Xian CHEN, Hua Liang JIANG, Guo Zhang JIN, Ru Yun JI. STUDIES ON DOPAMINE RECEPTORS AND TETRAHYDROPROTOBERBERINES.Ⅲ.3D-QSAR STUDY ON TETRAHYDROPROTOBERBERINES USING COMFA APPROACH[J]. Chinese Chemical Letters, ;1996, 7(3): 249-252. shu

STUDIES ON DOPAMINE RECEPTORS AND TETRAHYDROPROTOBERBERINES.Ⅲ.3D-QSAR STUDY ON TETRAHYDROPROTOBERBERINES USING COMFA APPROACH

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 294 Taiyuan Road, Shanghai 200031

Received Date: 11 July 1995

Fund Project: This work was supported by lire Chinese National "863" High Technology Project (No. 863-103-22-02) and the Chinese National Natural Science Foundation Key Project (No. 39130091).

Using comparative molecular field analysis approach,the interaction of 17 tetrahydroprotoberberines to D₁ receptor and 15 ones to D₂ receptor have been studied by 3D-QSAR,respectively.The results indicated that the interactions of THPBs with dopamine receptors were primarily electrostatic interactions,with more positive charge in ligand and more negative in receptor.
1. [1]
  Ao Sun , Zipeng Li , Shuchun Li , Xiangbao Meng , Zhongtang Li , Zhongjun Li . Stereoselective synthesis of α-3-deoxy-D-manno-oct-2-ulosonic acid (α-Kdo) derivatives using a C3-p-tolylthio-substituted Kdo fluoride donor. Chinese Chemical Letters, 2025, 36(3): 109972-. doi: 10.1016/j.cclet.2024.109972
2. [2]
  Jieyu Liu , Junze Zhang , Haigang Deng , Shuoao Wang , Xingxing Jiang , Li Wang , Changhong Wang . Understanding the activity origin of Pd-anchored single-atom alloy catalysts for NO-to-NH₃ conversion by DFT studies and machine learning. Chinese Chemical Letters, 2025, 36(12): 110656-. doi: 10.1016/j.cclet.2024.110656
3. [3]
  Lanyun Zhang , Weisi Wang , Yu-Qiang Zhao , Rui Huang , Yuxun Lu , Ying Chen , Liping Duan , Ying Zhou . Mechanism study of the molluscicide candidate PBQ on Pomacea canaliculata using a viscosity-sensitive fluorescent probe. Chinese Chemical Letters, 2025, 36(1): 109798-. doi: 10.1016/j.cclet.2024.109798
4. [4]
  Honglin Chen , Rupeng Wang , Zixiang He , Shih-Hsin Ho . Data-driven insights into nonradical activation mechanisms for biochar inverse design: A synergistic approach using DFT and machine learning with meta-analysis. Chinese Chemical Letters, 2026, 37(2): 111372-. doi: 10.1016/j.cclet.2025.111372
5. [5]
  Chaozheng He , Jia Wang , Ling Fu , Wei Wei . Nitric oxide assists nitrogen reduction reaction on 2D MBene: A theoretical study. Chinese Chemical Letters, 2024, 35(5): 109037-. doi: 10.1016/j.cclet.2023.109037
6. [6]
  Yujia Shi , Yan Qiao , Pengfei Xie , Miaomiao Tian , Xingwei Li , Junbiao Chang , Bingxian Liu . Rhodium-catalyzed enantioselective in situ C(sp³)−H heteroarylation by a desymmetrization approach. Chinese Chemical Letters, 2024, 35(10): 109544-. doi: 10.1016/j.cclet.2024.109544
7. [7]
  Honglin Gao , Chunlin Yuan , Hongyu Chen , Aiyi Dong , Pan Gao , Guangjin Hou . Surface gallium hydride on Ga2O3 polymorphs: A comparative solid-state NMR study. Chinese Journal of Structural Chemistry, 2025, 44(4): 100561-100561. doi: 10.1016/j.cjsc.2025.100561
8. [8]
  Qi Zhang , Bin Han , Yucheng Jin , Mingrun Li , Enhui Zhang , Jianzhuang Jiang . 2D and 3D phthalocyanine covalent organic frameworks for electrocatalytic carbon dioxide reduction. Chinese Chemical Letters, 2025, 36(9): 110330-. doi: 10.1016/j.cclet.2024.110330
9. [9]
  Yuexi Guo , Zhaoyang Li , Jingwei Dai . Charlie and the 3D Printing Chocolate Factory. University Chemistry, 2024, 39(9): 235-242. doi: 10.3866/PKU.DXHX202309067
10. [10]
  Jingwen Wang , Peizhang Zhao , Mengmeng Li , Jun Li , Yunfeng Lin . Remedying infectious bone defects via 3D printing technology. Chinese Chemical Letters, 2025, 36(9): 110686-. doi: 10.1016/j.cclet.2024.110686
11. [11]
  Xin Zhang , Zhihao Lu , Tianci Ren , Junxiang Tang , Shuo Li , Chenghao Zhu , Lijun Mao , Da Ma . Fluorescent "Texas-sized" macrocyclic receptors for the recognition and detection of nucleotides in water. Chinese Chemical Letters, 2025, 36(11): 110946-. doi: 10.1016/j.cclet.2025.110946
12. [12]
  Gaorong Wu , Tao Ma . Recent advanced in C–H borylation using BX₃ with different directing group auxiliary. Chinese Chemical Letters, 2026, 37(3): 111739-. doi: 10.1016/j.cclet.2025.111739
13. [13]
  Chenghao Liu , Xiaofeng Lin , Jing Liao , Min Yang , Min Jiang , Yue Huang , Zhizhi Du , Lina Chen , Sanjun Fan , Qitong Huang . Carbon dots-based dopamine sensors: Recent advances and challenges. Chinese Chemical Letters, 2024, 35(12): 109598-. doi: 10.1016/j.cclet.2024.109598
14. [14]
  Yang Li , Yanan Dong , Zhihong Wei , Changzeng Yan , Zhen Li , Lin He , Yuehui Li . Fluoride-promoted Ni-catalyzed cyanation of C–O bond using CO₂ and NH₃. Chinese Chemical Letters, 2025, 36(5): 110206-. doi: 10.1016/j.cclet.2024.110206
15. [15]
  Jiawei Hu , Kai Xia , Ao Yang , Zhihao Zhang , Wen Xiao , Chao Liu , Qinfang Zhang . Interfacial Engineering of Ultrathin 2D/2D NiPS₃/C₃N₅ Heterojunctions for Boosting Photocatalytic H₂ Evolution. Acta Physico-Chimica Sinica, 2024, 40(5): 2305043-0. doi: 10.3866/PKU.WHXB202305043
16. [16]
  Jie XIE , Hongnan XU , Jianfeng LIAO , Ruoyu CHEN , Lin SUN , Zhong JIN . Nitrogen-doped 3D graphene-carbon nanotube network for efficient lithium storage. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1840-1849. doi: 10.11862/CJIC.20240216
17. [17]
  Xi Xu , Chaokai Zhu , Leiqing Cao , Zhuozhao Wu , Cao Guan . Experiential Education and 3D-Printed Alloys: Innovative Exploration and Student Development. University Chemistry, 2024, 39(2): 347-357. doi: 10.3866/PKU.DXHX202308039
18. [18]
  Qiang Zhou , Pingping Zhu , Wei Shao , Wanqun Hu , Xuan Lei , Haiyang Yang . Innovative Experimental Teaching Design for 3D Printing High-Strength Hydrogel Experiments. University Chemistry, 2024, 39(6): 264-270. doi: 10.3866/PKU.DXHX202310064
19. [19]
  Changyuan Bao , Yunpeng Jiang , Haoyin Zhong , Huaizheng Ren , Junhui Wang , Binbin Liu , Qi Zhao , Fan Jin , Yan Meng Chong , Jianguo Sun , Fei Wang , Bo Wang , Ximeng Liu , Dianlong Wang , John Wang . Synergizing 3D-printed structure and sodiophilic interface enables highly efficient sodium metal anodes. Chinese Chemical Letters, 2024, 35(11): 109353-. doi: 10.1016/j.cclet.2023.109353
20. [20]
  Chengmin Hu , Pingxuan Liu , Ziyang Song , Yaokang Lv , Hui Duan , Li Xie , Ling Miao , Mingxian Liu , Lihua Gan . Tailor-made overstable 3D carbon superstructures towards efficient zinc-ion storage. Chinese Chemical Letters, 2025, 36(4): 110381-. doi: 10.1016/j.cclet.2024.110381

Get Citation

PDF

XML

Metrics

PDF Downloads(1)
Abstract views(1467)
HTML views(26)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Address：Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888

DownLoad: Full-Size Img PowerPoint

Return