Citation: Zhao Lou YU, Li Wen CHANG, Tian Sheng SU. CAPILLARY ELECTROPHORETIC SEPARATION OF GANGLIOSIDES USING CYCLODEXTRIN AS BUFFER ADDITIVE[J]. Chinese Chemical Letters, ;1993, 4(9): 827-828. shu

CAPILLARY ELECTROPHORETIC SEPARATION OF GANGLIOSIDES USING CYCLODEXTRIN AS BUFFER ADDITIVE

Institute of Chemistry, Academia Sinica, Beijing, 100080

Received Date: 31 May 1993

A new method for the rapid separation of gangliosides (GLS) by capillary electrophoresis (CE) is described which is based on the use of β—cyclodextrin (β—CD) as buffer additive.The effects of β—CD concentration, pH, electrolyte composition were discussed.Under optimum conditions, the complete separation of a mixture of GM1, GD1a, GD1b and GT1b was obtained within 5 min.
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