Citation:
Wei Ping YIN, Tian Zeng ZHAO, Ling Jie GAO, Da Peng ZOU, Jian Xun KANG. A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities[J]. Chinese Chemical Letters,
;1999, 10(6): 487-490.
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A new sesquiterpene polyol ester was isolated from the leaves of Celastrus angulatus. Its structure was determined as 1β, 2β,9α-triacetoxy-8α-(α-hydroxyl-isobutyryloxy)-15-benzoyloxy-4α-hydroxy-dihydroagarofuran by means of NMR, MS and IR spectral analysis. Preliminary biological study on antitumor activity revealed that this compound showed strong nonselective cytotoxicity against four of the NCI panel cell lines.
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