Citation: Wei LIU, Yuan MA, Ying Wu YIN, Yu Fen ZHAO. Improved Electrochemical Synthesis of Nitro-substituted 1-Aryl-2-pyrrolidinecarbonitriles[J]. Chinese Chemical Letters, ;2006, 17(6): 736-738. shu

Improved Electrochemical Synthesis of Nitro-substituted 1-Aryl-2-pyrrolidinecarbonitriles

Wei LIU ^1, ,
Yuan MA ¹ ,
Ying Wu YIN ^2,3 ,
Yu Fen ZHAO ¹

1.
The Key Laboratory for Bioorganic Phosphorus Chemistry & Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084;
2.
Department of Chemistry, Tsinghua University, Beijing 100084;
3.
Beijing TH-UNIS Insight Co. Ltd., Beijing 100084

Received Date: 19 December 2005

Fund Project: The authors would like to thank the financial support of Beijing TH-UNIS-Insight Co. Ltd. and the National Natural Science Foundation of China (No.20132020), the Ministry of Science and Technology, the Chinese Ministry of Education and Tsinghua University.

In this paper, we described an improved electrochemical method for synthesis of some1-aryl-2-pyrrolidinecarbonitrile derivatives bearing an electron-withdrawing group (NO₂). The electrochemical synthesis of titile compounds has been successfully performed in an undivided cell in reasonable yields.
- Anodic cyanation,
- nitrile,
- pyrrolidine,
- electrochemistry
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