Citation:
Feng LIU, Feng Hua LIU, Guo Liang TAO, Rem Xi ZHUO. SYNTHESES OF Ph AND TEMPERATURE-SENSITIVE HYDROGELS AND THEIR APPLICATIONS IN CONTROLLED RELEASE OF BIOMACROMOLECULES[J]. Chinese Chemical Letters,
;1995, 6(1): 35-38.
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A series of pH-and temperature-sensitive hydrogels were prepared.These gels do not swell at 37℃ and pH 1.4 but swell at 37℃ and pH 7.4.When papain was loaded in these gels,it can be released at 37℃ and pH 7.4 in a high percentage without any loss of activity.
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