Citation: Rui Yun GUO, Jun Biao CHANG, Rong Feng CHEN, Jing Xi XIE. Synthesis of Novel Nucleoside:2'-deoxyuridine-3',5'-di(4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybipheny1-2-methoxy carbonyl 2'-carboxylate)[J]. Chinese Chemical Letters, ;1999, 10(5): 341-344. shu

Synthesis of Novel Nucleoside:2'-deoxyuridine-3',5'-di(4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybipheny1-2-methoxy carbonyl 2'-carboxylate)

Henan Institute of Chemistry, Zhengzhou 450003

Received Date: 14 September 1998

Abstract:Hepatitis B Virus (HBV) belongs to the family of hepadnaviridae which comprises several animal viruses, including human HBV, woodchuck hepatitis (WHV), ground squirrel hepatitis virus (GSHV) and duck hepatitis B virus (DHBV). These viruses share common features such as the genome organization, mode of replication and similar tropism for hepatocytes¹. 2'-deoxyuridine-substituted biphenyl carboxylate was synthesized as anti-hepatitis B agents. The structure was confirmed by UV, ¹HNMR spectrum and elementary analysis.
- 2'-Deoxyuridine biphenyl carboxylate,
- biphenyl,
- 2'-deoxyuridine
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