Citation: Guang Yi JIN, Xu Chang HE, Hai Yan ZHANG, Dong Lu BAI. Synthesis of Alkylene-linked Dimers of (-)-Huperzine A[J]. Chinese Chemical Letters, ;2002, 13(1): 23-26. shu

Synthesis of Alkylene-linked Dimers of (-)-Huperzine A

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031

Received Date: 21 May 2001

Fund Project: This work was partially supported by the National Natural Science Foundation of China.

Six alkylene-linked dimers of (-)-huperzineA (6) were prepared.All these dimers are less potent than (-)-Hup A in inhibition of AChE.
- Alkylene-linked dimers,
- (-)-huperzineA,
- Acetylcholinesterase
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