Citation: E.O. Moradi Rufchahi, H. Pouramir, M.R. Yazdanbakhsh, H. Yousefi, M. Bagheri, M. Rassa. Novel azo dyes derived from 8-methyl-4-hydroxyl-2-quinolone：Synthesis, UV-vis studies and biological activity[J]. Chinese Chemical Letters, ;2013, 24(05): 425-428. shu

Novel azo dyes derived from 8-methyl-4-hydroxyl-2-quinolone：Synthesis, UV-vis studies and biological activity

1.
a Department of Chemistry, Faculty of Science, Lahijan Branch, Islamic Azad University, Lahijan, Iran;
2.
b Department of Chemistry, Faculty of Sciences, University of Guilan, Rasht, Iran;
3.
c Department of Biology, Faculty of Sciences, University of Guilan, Rasht, Iran

Corresponding author: E.O. Moradi Rufchahi,
Received Date: 1 January 2013
Available Online: 20 February 2013

In this study, N,N'-di-(2-methylphenyl)malonamide was synthesized and reacted with polyphosphoric acid to afford 8-methyl-4-hydroxyl-2-quinolone. Eight novel azo disperse dyes were then synthesized by linking diazotized p-substituted aniline derivatives with 8-methyl-4-hydroxyl-2-quinolone. The solvatochromism of these azo dyes in various solvents was evaluated. All the compounds were then evaluated for their antibacterial activity against four bacteria, namely, Bacillus subtilis, Micrococcus luteus, Salmonella enterica, and Pseudomonas aeruginosa. The results showed that some of these compounds have high levels of antibacterial activity.
- Disperse dyes,
- Hydroxyl quinolone,
- Absorption spectrum,
- Antibacterial studies
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沈阳化工大学材料科学与工程学院沈阳 110142