Citation: Ke Dong, Jian-Xin Pu, Xue Du, Xiao-Nian Li, Han-Dong Sun. Two new guaianolide-type sesquiterpenoids from Kadsura interior[J]. Chinese Chemical Letters, ;2013, 24(2): 111-113. shu

Two new guaianolide-type sesquiterpenoids from Kadsura interior

1.
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China

Corresponding author: Jian-Xin Pu, Han-Dong Sun,
Received Date: 22 November 2012
Available Online: 26 December 2012
Fund Project:

Two new guaianolide-type sesquiterpenoids, 4β,9β-dihydroxy-1α,5α-H-guaia-6,10(14)-dien (1) and 4β,9β,10α-trihydroxy-1α,5α-H-guaia-6-en (2), along with four known sesquiterpenoids (3a, 3b, 4 and 5), were isolated from Kadsura interior. Their structures and configurations were elucidated by spectroscopicmethods including 2D-NMR and HR-MS techniques. Compounds 3a and 3b were obtained as a pair of enantiomers, and their structure and absolute configuration were established from their extensive NMR spectra and by single-crystal X-ray analysis.
- Kadsura interior,
- 4β,9β-Dihydroxy-1α,5α-H-guaia-6,10(14)-dien,
- 4β,9β,10α-Trihydroxy-1α,5α-H-guaia-6-en,
- X-ray technique
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  [12] C. Zou, X.Y. Pu, J. Zhou, Sesquiterpenoids from Kadsura ananosma, Acta Bot. Yunnanica 15 (1993) 196-200.
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  [13] F. Bohlmann, J. Jakupovic, Neue labdan-derivate und sesquiterpene aus Silphiumarten, Phytochemistry 18 (1979) 1987-1992.
14. [14]
  [14] Y. Oshima, T. Iwakawa, H. Hikino, Alismol and alismoxide, sesquiterpenoids of Alisma rhizomes, Phytochemistry 22 (1983) 183-185.
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  [15] K.A.E.I. Sayed, M.T. Hamann, A new norcembranoid dimer from the red sea soft coral Sinularia gardineri, J. Nat. Prod. 59 (1996) 687-689.
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  [16] B.F. Bowden, J.C. Coll, S.J. Mitchell, Studies of Australian soft corals. XXI. A new sesquiterpene from Nephthea chabrolii and an investigation of the common clam Tridacna maxima, Aust. J. Chem. 33 (1980) 1833-1839.
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Two new guaianolide-type sesquiterpenoids from Kadsura interior

References

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通讯作者: 陈斌, bchen63@163.com