Citation: Jin Song YANG, Kazuhiro KONDO, Yasuoki MURAKAMI. First Application of Optically Active trans-1,2-Bis(2-aminophenyl)cyclopentane for Asymmetric Reaction:Enantioselective N-Acetylation of Secondary Alkyl Amines[J]. Chinese Chemical Letters, ;2001, 12(1): 1-4. shu

First Application of Optically Active trans-1,2-Bis(2-aminophenyl)cyclopentane for Asymmetric Reaction:Enantioselective N-Acetylation of Secondary Alkyl Amines

1.
Department of Chemistry of Medicinal Natural Products School of Pharmacy West China University of Medical Sciences Chengdu 610041;
2.
School of Pharmaceutical Sciences Toho University Miyama 2-2-1 Funabashi Chiba 274 Japan

Received Date: 2 June 2000

First application of optically active trans-1,2-Bis(2-aminophenyl)cyclopentane 2 for asymmetric reaction, enantioselective N-acetylation of secondary alkyl amines, is described. This acetylation with tetraacetylated 3 which was prepared from 2, gave the N-acetylamines with up to 21% ee.
- Chiral,
- enantioselective N-acetylation
1. [1]
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