Citation: Xiao Ming FENG, Rong CHEN, Lian Fu TANG, Yao Zhong JIANG. Syntheses of (3-Benzyl-4-Aroyl-1,2,4-Triazole-5-yl)[5-(3,4,5-Trimethoxylphenyl)-1,3,4-Oxadizole-2-yl] Sulfides[J]. Chinese Chemical Letters, ;1997, 8(3): 195-198. shu

Syntheses of (3-Benzyl-4-Aroyl-1,2,4-Triazole-5-yl)[5-(3,4,5-Trimethoxylphenyl)-1,3,4-Oxadizole-2-yl] Sulfides

Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041

Received Date: 7 December 1996

Twelve new (3-benzyl-4-aroyl-1,2,4-triazole-5-yl)[5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole-2-yl] sulfides(2) have been synthesized from the nucieophilic displacements of 3-benzyl-4-aroyl-1,2,4-triazole-5-hydrosulfuryl anion on the 2-position of 2-methylsulfonyl-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole(1).Compounds(2) were screened for their antibacterial activity against E.Coli at 0.01%.The results show that some compounds(2) have strong inhibiting effects.
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