Citation: QU Di, LIU Zhen, LI Jing, LUO Xiao-Xing, LI Ming-Kai. Synthesis and Antibacterial Activities of Pyran Annulated Heterocyclic Compounds[J]. Chinese Journal of Structural Chemistry, ;2015, 34(2): 185-188. doi: 10.14102/j.cnki.0254-5861.2011-0443 shu

Synthesis and Antibacterial Activities of Pyran Annulated Heterocyclic Compounds

QU Di ^a ,
LIU Zhen ^b ,
LI Jing ^b ,
LUO Xiao-Xing ^a ,
LI Ming-Kai ^a,,

a.
a. Department of Pharmacology, School of Pharmacy, the Fourth Military Medical University, Xi'an 710032, China;
b.
b. School of Chemistry and Chemical Engineering, Xi'an University, Xi'an 710065, China

Corresponding author: LI Ming-Kai,
Received Date: 7 July 2014
Available Online: 18 December 2014
Fund Project:

Two novel pyran annulated heterocyclic compounds (1 and 2) were synthesized and characterized via IR, ¹H NMR and H RMS. The structure of compound 1 was verified by single-crystal X-ray diffraction. The in vitro antibacterial activities of the two compounds against Staphylococcus aureus (S. aureus ATCC 29213), methicillin-resistant S. aureus (MRSA XJ 75302), vancomycin-intermediate S. aureus (Mu50 ATCC 700699), and USA 300 (Los Angeles County clone, LAC) were evaluated by observing the minimum inhibitory concentration.
- pyran,
- crystal,
- Staphylococcus aureus,
- minimum inhibitory concentration
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