Citation: Jingwen Wang, Peizhang Zhao, Mengmeng Li, Jun Li, Yunfeng Lin. Remedying infectious bone defects via 3D printing technology[J]. Chinese Chemical Letters, ;2025, 36(9): 110686. doi: 10.1016/j.cclet.2024.110686 shu

Remedying infectious bone defects via 3D printing technology

Jingwen Wang ^{a, b} ,
Peizhang Zhao ^{a, b} ,
Mengmeng Li ^{a, b} ,
Jun Li ^{a, b, *,} ,
Yunfeng Lin ^{c, d, *,}

a.
Orthopedic Research Institute, Department of Orthopedics, West China Hospital, Sichuan University, Chengdu 610041, China
b.
Trauma Center, West China Hospital, Sichuan University, Chengdu 610041, China
c.
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
d.
Sichuan Provincial Engineering Research Center of Oral Biomaterials, Chengdu 610041, China

mrorthopedics@sina.com

yunfenglin@scu.edu.cn

Received Date: 6 August 2024
Revised Date: 20 November 2024
Accepted Date: 26 November 2024
Available Online: 28 November 2024

Figures(4)

The technology of three dimensional (3D) printing, also known as additive manufacturing, is a cutting-edge type of fabrication method that utilizes a computer-aided design platform and employs layer-by-layer stacking to construct objects with exceptional flexibility. Due to its capacity to produce a substantial quantity of products within a short period of time, 3D printing has emerged as one of the most significant manufacturing technology. Over the past two decades, remarkable advancements have been made in the application of 3D printing technology in the realm of bone tissue engineering. This review presents an innovative and systematic discussion on the potential application of 3D printing technology in bone tissue engineering, particularly in the treatment of infected bone defects. It comprehensively evaluates the materials utilized in 3D printing, highlights the interplay between cells and bone regeneration, and addresses and resolves challenges associated with current 3D printing technology. These challenges include material selection, fabrication of intricate 3D structures, integration of different cell types, streamlining design processes and material selection procedures, enhancing the clinical translational potential of 3D printing technology, and ultimately exploring future applications of four dimensional (4D) printing technology. The 3D printing technology has demonstrated significant potential in the synthesis of bone substitutes, offering consistent mechanical properties and ease of use. It has found extensive applications in personalized implant customization, prosthetic limb manufacturing, surgical tool production, tissue engineering, biological modeling, and cell diagnostics. Simultaneously, 3D bioprinting provides an effective solution to address the issue of organ donor shortage. However, challenges still exist in material selection, management of structural complexity, integration of different cell types, and construction of functionally mature tissues. With advancements in multi-material printing techniques as well as bioprinting and 4D printing technologies emerging on the horizon; 3D printing holds immense prospects for revolutionizing the means by which infectious bone defects are repaired.
- 3D printing technology,
- Infectious bone defect,
- Bio-ink,
- Bone scaffold,
- Smart material,
- Mesenchymal stem cell
1. [1]
  E.A. Masters, B.F. Ricciardi, K.L.M. Bentley, et al., Nat. Rev. Microbiol. 20 (2022) 385–400. doi: 10.1038/s41579-022-00686-0
2. [2]
  A.L. Foster, J. Warren, K. Vallmuur, et al., Bone Joint J. 106-b (2024) 77–85. doi: 10.1302/0301-620x.106b1.bjj-2023-0279.r2
3. [3]
  Q. Wu, J. Shi, J. Huang, et al., Infect. Drug Resist. 16 (2023) 6395–6404. doi: 10.2147/idr.s427836
4. [4]
  D. Fan, Y. Liu, Y. Wang, et al., Front. Pharmacol. 13 (2022) 1044726. doi: 10.3389/fphar.2022.1044726
5. [5]
  S. Hong, W. Jiang, Q. Ding, et al., Int. J. Nanomedicine 18 (2023) 3761–3780. doi: 10.2147/ijn.s403882
6. [6]
  S. Tian, L. Su, Y. Liu, et al., Sci. Adv. 6 (2020) eabb1112. doi: 10.1126/sciadv.abb1112
7. [7]
  H.P. Bei, P.M. Hung, H.L. Yeung, et al., Small 17 (2021) e2101741. doi: 10.1002/smll.202101741
8. [8]
  M. Zhang, R. Lin, X. Wang, et al., Sci. Adv. 6 (2020) eaaz6725. doi: 10.1126/sciadv.aaz6725
9. [9]
  W. Sun, Z. Liu, J. Xu, et al., Chin. Chem. Lett. 34 (2023) 107819. doi: 10.1016/j.cclet.2022.107819
10. [10]
  C. Zhang, G. Wang, H. Lin, et al., Cell Prolif. 56 (2023) e13417. doi: 10.1111/cpr.13417
11. [11]
  T. Potyondy, J.A. Uquillas, P.J. Tebon, et al., Biofabrication 13 (2021) 022001. doi: 10.1088/1758-5090/abc8de
12. [12]
  E. Ning, G. Turnbull, J. Clarke, et al., Biofabrication 11 (2019) 045018. doi: 10.1088/1758-5090/ab37a0
13. [13]
  W. Dai, M. Sun, X. Leng, et al., Front. Bioeng. Biotechnol. 8 (2020) 604814. doi: 10.3389/fbioe.2020.604814
14. [14]
  L. Ouyang, J.P.K. Armstrong, Y. Lin, et al., Sci. Adv. 6 (2020) eabc5529. doi: 10.1126/sciadv.abc5529
15. [15]
  J.M. Bliley, D.J. Shiwarski, A.W. Feinberg, Sci. Transl. Med. 14 (2022) eabo7047. doi: 10.1126/scitranslmed.abo7047
16. [16]
  M.E. Kupfer, W.H. Lin, V. Ravikumar, et al., Circ. Res. 127 (2020) 207–224. doi: 10.1161/circresaha.119.316155
17. [17]
  S.H. Kim, H. Hong, O. Ajiteru, et al., Nat. Protoc. 16 (2021) 5484–5532. doi: 10.1038/s41596-021-00622-1
18. [18]
  X. Hu, W. Zhao, Z. Zhang, et al., Chin. Chem. Lett. 34 (2023) 107451. doi: 10.1016/j.cclet.2022.04.049
19. [19]
  P. Kumar, S. Huang, D.H. Cook, et al., Nat. Commun. 15 (2024) 841. doi: 10.1038/s41467-024-45178-2
20. [20]
  D. Liu, Q. Yu, S. Kabra, et al., Science 378 (2022) 978–983. doi: 10.1126/science.abp8070
21. [21]
  Z. Wang, Y. Wang, J. Yan, et al., Adv. Drug Deliv. Rev. 174 (2021) 504–534. doi: 10.1016/j.addr.2021.05.007
22. [22]
  C.J. Todaro, M.A. Easton, D. Qiu, et al., Nat. Commun. 11 (2020) 142. doi: 10.1038/s41467-019-13874-z
23. [23]
  S. Wang, X. Zhao, Y. Hsu, et al., Acta Biomater. 169 (2023) 19–44. doi: 10.1117/12.2673256
24. [24]
  Y. Wei, Z. Liu, X. Zhu, et al., Biomaterials 257 (2020) 120237. doi: 10.1016/j.biomaterials.2020.120237
25. [25]
  X. Pan, M. Ou, Y. Lu, et al., Biomater. Adv. 152 (2023) 213503. doi: 10.1016/j.bioadv.2023.213503
26. [26]
  J.W. Park, T. Hanawa, J.H. Chung, Int. J. Nanomedicine 14 (2019) 5697–5711. doi: 10.2147/ijn.s214363
27. [27]
  M. Yao, S. Cheng, G. Zhong, et al., Bioact. Mater. 6 (2021) 2729–2741.
28. [28]
  X. Bai, W. Liu, L. Xu, et al., J. Mater. Chem. B 9 (2021) 2885–2898. doi: 10.1039/d0tb02884c
29. [29]
  N.H. Lee, M.S. Kang, T.H. Kim, et al., Biomaterials 276 (2021) 121025. doi: 10.1016/j.biomaterials.2021.121025
30. [30]
  R. Qiao, S.Y. Tang, Science 378 (2022) 594–595. doi: 10.1126/science.ade1813
31. [31]
  L. Zhang, X. Huang, T. Cole, et al., Nat. Commun. 14 (2023) 7815. doi: 10.1038/s41467-023-43667-4
32. [32]
  C.P. Ambulo, M.J. Ford, K. Searles, et al., ACS Appl. Mater. Interfaces 13 (2021) 12805–12813. doi: 10.1021/acsami.0c19051
33. [33]
  H. Kim, S.K. Ahn, D.M. Mackie, et al., Mater. Today 41 (2020) 243–269. doi: 10.1016/j.mattod.2020.06.005
34. [34]
  L. Chen, Z. Yan, T. Qiu, et al., ACS Appl. Bio Mater. 6 (2023) 4703–4713. doi: 10.1021/acsabm.3c00488
35. [35]
  B. Jia, H. Yang, Z. Zhang, et al., Bioact. Mater. 6 (2021) 1588–1604.
36. [36]
  D. Jain, S. Pareek, A. Agarwala, et al., J. Mater. Res. Technol. 10 (2021) 738–751. doi: 10.1016/j.jmrt.2020.12.050
37. [37]
  G. Parande, V. Manakari, S.D. Sharma Kopparthy, et al., Compos. B: Eng. 182 (2020) 107650. doi: 10.1016/j.compositesb.2019.107650
38. [38]
  H. Yang, B. Jia, Z. Zhang, et al., Nat. Commun. 11 (2020) 401. doi: 10.1038/s41467-019-14153-7
39. [39]
  J. Wang, H. Xia, X. Fan, et al., Mol. Biotechnol. 64 (2022) 928–935. doi: 10.1007/s12033-022-00474-4
40. [40]
  H. Wu, X. Xie, J. Wang, et al., J. Mater. Res. Technol. 13 (2021) 1779–1789. doi: 10.1016/j.jmrt.2021.05.096
41. [41]
  H. Yuk, B. Lu, S. Lin, et al., Nat. Commun. 11 (2020) 1604. doi: 10.1038/s41467-020-15316-7
42. [42]
  J. Li, C. Parra-Cantu, Z. Wang, et al., Trends Cancer 6 (2020) 745–756. doi: 10.1016/j.trecan.2020.06.002
43. [43]
  J. Bauer, C. Crook, T. Baldacchini, Science 380 (2023) 960–966. doi: 10.1126/science.abq3037
44. [44]
  M. Mader, O. Schlatter, B. Heck, et al., Science 372 (2021) 182–186. doi: 10.1126/science.abf1537
45. [45]
  T. Ayode Otitoju, P. Ugochukwu Okoye, G. Chen, et al., J. Ind. Eng. Chem. 85 (2020) 34–65. doi: 10.1016/j.jiec.2020.02.002
46. [46]
  W. Zhai, L. Bai, R. Zhou, et al., Adv. Sci. 8 (2021) e2003739. doi: 10.1002/advs.202003739
47. [47]
  Y. Zhao, H. Mei, P. Chang, et al., Compos. B: Eng. 221 (2021) 109013. doi: 10.1016/j.compositesb.2021.109013
48. [48]
  A. Marques, G. Miranda, F. Silva, et al., J. Biomed. Mater. Res. B: Appl. Biomater. 109 (2021) 377–393. doi: 10.1002/jbm.b.34706
49. [49]
  S. Behseresht, A. Love, O.A. Valdez Pastrana, et al., Materials 17 (2024) 109414.
50. [50]
  Y. Qi, H. Lv, Q. Huang, et al., Eur. Polym. J. 213 (2024) 113133. doi: 10.1016/j.eurpolymj.2024.113133
51. [51]
  Q.Y. Yao, M.L. Fu, Q. Zhao, et al., World J. Clin. Cases 11 (2023) 5047–5055. doi: 10.12998/wjcc.v11.i21.5047
52. [52]
  H. Budharaju, S. Suresh, M.P. Sekar, et al., Mater. Des. 231 (2023) 112064. doi: 10.1016/j.matdes.2023.112064
53. [53]
  H.Kolahi Azar, M. Hajian Monfared, A.A. Seraji, et al., Int. J. Biol. Macromol. 258 (2024) 128482. doi: 10.1016/j.ijbiomac.2023.128482
54. [54]
  A. Ameri, H.M. Ahmed, R.D.C. Pecho, et al., Cancer Cell Int. 23 (2023) 261.
55. [55]
  S. Mirabdali, K. Ghafouri, Y. Farahmand, et al., Pathol. Res. Pract. 253 (2024) 154899. doi: 10.1016/j.prp.2023.154899
56. [56]
  Z. Li, X. Zhang, J. Ouyang, et al., Bioact. Mater. 6 (2021) 4053–4064.
57. [57]
  G. Zeng, Y. Chen, Acta Biomater. 118 (2020) 1–17. doi: 10.1155/2020/8843524
58. [58]
  X. Zhang, I.S. Donskyi, W. Tang, et al., Angew. Chem. Int. Ed. 62 (2023) e202213336.
59. [59]
  C. He, F. Ruan, S. Jiang, et al., Small 16 (2020) e2001371.
60. [60]
  P. Subramanian, B. Dutta, A. Arya, et al., J. Pharm. Bioallied Sci. 16 (2024) S17–S19. doi: 10.4103/jpbs.jpbs_550_23
61. [61]
  H. Wei, J. Cui, K. Lin, et al., Bone Res. 10 (2022) 17. doi: 10.54097/fbem.v6i3.3111
62. [62]
  L. Li, Z. Zeng, Z. Chen, et al., ACS Nano 14 (2020) 15403–15416. doi: 10.1021/acsnano.0c06000
63. [63]
  D. Li, K. Chen, H. Tang, et al., Adv. Mater. 34 (2022) e2108430.
64. [64]
  N. Li, L. Liu, C. Wei, et al., ACS Appl. Mater. Interfaces 14 (2022) 53523–53534. doi: 10.1021/acsami.2c16774
65. [65]
  W. Chen, H. Zhang, Q. Zhou, et al., Research 6 (2023) 0089.
66. [66]
  W. Wang, J. Li, Z. Zhang, et al., Cell Prolif. 54 (2021) e12951.
67. [67]
  X. Yuan, W. Zhu, Z. Yang, et al., Adv. Mater. 36 (2024) e2403641.
68. [68]
  Z. Li, S. Li, J. Yang, et al., Carbohydr. Polym. 290 (2022) 119469.
69. [69]
  A. Abaci, M. Guvendiren, Biofabrication 16 (2024) 035027. doi: 10.1088/1758-5090/ad52f1
70. [70]
  W. Tessanan, P. Daniel, P. Phinyocheep, ACS Omega 6 (2021) 14838–14847. doi: 10.1021/acsomega.1c00418
71. [71]
  Y. Song, J. Zhang, H. Xu, et al., J. Orthop. Translat. 24 (2020) 121–130.
72. [72]
  S.M. Santillán-Guaján, M.H. Shahi, J.S. Castresana, Cells 13 (2024) 617. doi: 10.3390/cells13070617
73. [73]
  A. Bajetto, S. Thellung, I. Dellacasagrande, et al., Stem Cells Transl. Med. 9 (2020) 1310–1330. doi: 10.1002/sctm.20-0161
74. [74]
  V. Fitzpatrick, Z. Martín-Moldes, A. Deck, et al., Biomaterials 276 (2021) 120995.
75. [75]
  W. Yan, M. Maimaitimin, Y. Wu, et al., Sci. Adv. 9 (2023) eadg8138.
76. [76]
  J. Deng, X. Wang, W. Zhang, et al., Adv. Funct. Mater. 33 (2023) 2211664.
77. [77]
  Q. Lin, X. Lin, Biotechnol. J. 18 (2023) e2300070.
78. [78]
  H. Hong, Y.B. Seo, D.Y. Kim, et al., Biomaterials 232 (2020) 119679.
79. [79]
  S. Zhao, J. Chen, L. Wu, et al., Int. J. Mol. Sci. 24 (2023) e2211510120.
80. [80]
  S.R. Lamandé, E.S. Ng, T.L. Cameron, et al., Proc. Natl. Acad. Sci. U. S. A. 120 (2023) e2211510120.
81. [81]
  H. Okano, S. Morimoto, Cell Stem Cell 29 (2022) 189–208.
82. [82]
  F. Varzideh, J. Gambardella, U. Kansakar, et al., Int. J. Mol. Sci. 24 (2023) 793–800.
83. [83]
  S. Abdelrahman, W.F. Alsanie, Z.N. Khan, et al., Biofabrication 14 (2022) 6963.
84. [84]
  L. Edgar, T. Pu, B. Porter, et al., Br. J. Surg. 107 (2020) 793–800. doi: 10.1002/bjs.11686
85. [85]
  Z. Li, D. He, B. Guo, et al., Nat. Commun. 14 (2023) 6963.
86. [86]
  K. Yuan, Y. Yang, Y. Lin, et al., Adv. Sci. (2024), doi: 10.1002/advs.202404453. doi: 10.1002/advs.202404453
87. [87]
  H. Wang, X. Liu, Q. Gu, et al., Cell Prolif. 56 (2023) e13453.
88. [88]
  M.A. Ortega, D. De Leon-Oliva, D. Liviu Boaru, et al., Histol. Histopathol. (2024), doi: 10.14670/HH-18-763. doi: 10.14670/HH-18-763
89. [89]
  W. Lan, X. Huang, D. Huang, X. Wei, W. Chen, J. Mater. Sci. 57 (2022) 12685–12709. doi: 10.1007/s10853-022-07361-y
90. [90]
  V. Chopra, V. Fuentes-Velasco, S.R. Nacif-Lopez, et al., Ceram. Int. (2024), doi: 10.1016/j.ceramint.2024.07.266. doi: 10.1016/j.ceramint.2024.07.266
91. [91]
  I. Matai, G. Kaur, A. Seyedsalehi, et al., Biomaterials 226 (2020) 119536.
92. [92]
  B. Li, M. Zhang, Q. Lu, et al., Biomed. Res. Int. 2022 (2022) 8759060.
93. [93]
  Z. Jin, Y. Li, K. Yu, et al., Adv. Sci. 8 (2021) e2101394.
94. [94]
  K.Prem Ananth, N.D. Jayram, Ann. 3D Print. Med. 13 (2024) 100141.
95. [95]
  L. Zhao, X. Wang, H. Xiong, et al., J. Eur. Ceram. Soc. 41 (2021) 5066–5074.
96. [96]
  Y. Wang, T. Wu, G. Huang, Mater. Today Commun. 40 (2024) 110001.
97. [97]
  Z. Wu, C. Shi, Y. Li, et al., Chem. Eng. J. 464 (2023) 142778.
98. [98]
  Y. Song, Y. Ghafari, A. Asefnejad, et al., Opt. Laser Technol. 171 (2024) 142778.
99. [99]
  Y. Bozkurt, E. Karayel, J. Mater. Res. Technol. 14 (2021) 1430–1450.
100. [100]
  K. Wang, J. Yin, X. Chen, et al., J. Alloys Compd. 975 (2024) 172821.
101. [101]
  D. Bhardwaj, R. Singhmar, M. Garg, et al., Eur. Polym. J. 205 (2024) 112736.
102. [102]
  Z. Li, J. Li, H. Luo, et al., J. Eur. Ceram. Soc. 42 (2022) 3841–3847. doi: 10.3390/cells11233841
103. [103]
  H. Chen, L. Guo, W. Zhu, et al., Polymers 14 (2022) 4635. doi: 10.3390/polym14214635
104. [104]
  O. Santoliquido, F. Camerota, A. Rosa, et al., Open Ceramics 5 (2021) 100089.
105. [105]
  M. Pagac, J. Hajnys, Q.-P. Ma, et al., Polymers 13 (2021) 598. doi: 10.3390/polym13040598
106. [106]
  J. Li, Y.X. Lai, M.X. Li, et al., Chem. Eng. J. 435 (2022) 134855.
107. [107]
  H. Liang, H. Zhang, B. Chen, et al., Sci. Rep. 13 (2023) 22667.
108. [108]
  A. Haleem, M. Javaid, R.H. Khan, et al., J. Clin. Orthop. Trauma 11 (2020) S118–S124.
109. [109]
  U.L. Lee, J.Y. Lim, S.N. Park, et al., Materials 13 (2020) 4515. doi: 10.3390/ma13204515
110. [110]
  M. Shahrezaie, A. Zamanian, M. Sahranavard, et al., Bioprinting 37 (2024) e00327.
111. [111]
  C. Faldini, A. Mazzotti, C. Belvedere, et al., J. Orthop. Traumatol. 21 (2020) 16.
112. [112]
  D.W. Wu, J.W. Tan, L.Y. Yao, et al., Compos. A: Appl. Sci. Manuf. 147 (2021) 106468.
113. [113]
  L. Li, J. Shi, K. Ma, et al., J. Adv. Res. 30 (2021) 75–84.
114. [114]
  C. Xu, Z. Liu, X. Chen, et al., Chin. Chem. Lett. 35 (2024) 109197.
115. [115]
  I. Seoane-Viaño, S.J. Trenfield, A.W. Basit, et al., Adv. Drug Deliv. Rev. 174 (2021) 553–575.
116. [116]
  H. Xie, K.K. Yang, Y.Z. Wang, Prog. Polym. Sci. 95 (2019) 32–64.
117. [117]
  X. Chen, S. Han, W. Wu, et al., Small 18 (2022) e2106824.
118. [118]
  P. Rastogi, B. Kandasubramanian, Chem. Eng. J. 366 (2019) 264–304.
1. [1]
  Yanjing Li , Jiayin Li , Yuqi Chang , Yunfeng Lin , Lei Sui . Tetrahedral framework nucleic acids promote the proliferation and differentiation potential of diabetic bone marrow mesenchymal stem cell. Chinese Chemical Letters, 2024, 35(9): 109414-. doi: 10.1016/j.cclet.2023.109414
2. [2]
  Xin Zhang , Junyu Chen , Xiang Pei , Linxin Yang , Liang Wang , Luona Chen , Guangmei Yang , Xibo Pei , Qianbing Wan , Jian Wang . Drug-loading ZIF-8 for modification of microporous bone scaffold to promote vascularized bone regeneration. Chinese Chemical Letters, 2024, 35(6): 108889-. doi: 10.1016/j.cclet.2023.108889
3. [3]
  Ruijianghan Shi , Yujie Zhu , Weitong Lu , Yuhan Shao , Yang Chen , Mi Zhou , Yunfeng Lin , Sirong Shi . Tetrahedral framework nucleic acids enhance osteogenic differentiation and prevent apoptosis for dental follicle stem cell therapy in diabetic bone repair. Chinese Chemical Letters, 2025, 36(5): 110241-. doi: 10.1016/j.cclet.2024.110241
4. [4]
  Dechao Yuan , Tianying Luo , Qiao Su , Changxing Qu , Meng Pan , Jia Xu , Mingyi Zhang , Yuanchao Luo , Renjian He , Shiwei Liu , Xiang Fang , Hong Duan , Zhiyong Qian . Nanozyme-based catalytic therapeutics: Applications in infectious diseases, cancer therapy, and bone regeneration. Chinese Chemical Letters, 2026, 37(3): 111842-. doi: 10.1016/j.cclet.2025.111842
5. [5]
  Xu Luo , Jinwen Xiao , Qiming Yang , Xiaolong Lu , Qianjun Huang , Xiaojun Ai , Bo Li , Li Sun , Long Chen . Biomaterials for surgical repair of osteoporotic bone defects. Chinese Chemical Letters, 2025, 36(1): 109684-. doi: 10.1016/j.cclet.2024.109684
6. [6]
  Xiaodan Liang , Tong Tong , Caihong Xian , Jiyuan Du , Biying Tan , Liying Wang , Jingyi Hou , Jun Wu . Metal-based biomaterials for treating bone diseases. Chinese Chemical Letters, 2026, 37(4): 111140-. doi: 10.1016/j.cclet.2025.111140
7. [7]
  Peizhang Zhao , Mengmeng Li , Jingwen Wang , Jun Li , Yunfeng Lin . Targeting the immune microenvironment: A novel strategy for treating infected bone defects with hydrogels. Chinese Chemical Letters, 2026, 37(5): 111319-. doi: 10.1016/j.cclet.2025.111319
8. [8]
  Tianxu Zhang , Dexuan Xiao , Mi Zhou , Yunfeng Lin , Tao Zhang , Xiaoxiao Cai . Protective effect of osteogenic growth peptide functionalized tetrahedral DNA nanostructure on bone marrow and bone formation ability in chemotherapy-induced myelosuppressive mice. Chinese Chemical Letters, 2025, 36(8): 110594-. doi: 10.1016/j.cclet.2024.110594
9. [9]
  Yi Zhu , Jingyan Zhang , Yuchao Zhang , Ying Chen , Guanghui An , Ren Liu . Designing unimolecular photoinitiator by installing NHPI esters along the TX backbone for acrylate photopolymerization and their applications in coatings and 3D printing. Chinese Chemical Letters, 2024, 35(7): 109573-. doi: 10.1016/j.cclet.2024.109573
10. [10]
  Jielin Wang , Han Ye , Bozhuang Zhou , Zhen Pan , Yucai Li , Zhenyuan Wei , Bin Chai , Yizhou Gao , Xiaojian Ye , Jiangming Yu . Biomimetic nanofibrillar/hyaluronic acid hydrogels remodel the neuromodulatory microenvironment for enhanced bone regeneration. Chinese Chemical Letters, 2025, 36(5): 110133-. doi: 10.1016/j.cclet.2024.110133
11. [11]
  Qing-Ri Jin , Tian-Jiao Zhou , Ya-Ting Yao , Hai-Qing Yu , Hao-Bin Che , Meng-Meng Zhang , Chun-Hui Cui , Yi Wang , Cheng-Jun Li , Lei Xing , Hu-Lin Jiang . Icaritin-incorporated dual-sensitizing hydrogel for osteosarcoma doxorubicin treatment and bone regeneration. Chinese Chemical Letters, 2026, 37(6): 111539-. doi: 10.1016/j.cclet.2025.111539
12. [12]
  Zeyang Yao , Xinru You , Xudong Wang , Yunze Kang , Liying Wang , Ziji Zhang . Stem cell-based hydrogel for the repair and regeneration of cartilage. Chinese Chemical Letters, 2025, 36(8): 110607-. doi: 10.1016/j.cclet.2024.110607
13. [13]
  Chong-Yang Shi , Jian-Xing Gong , Zhen Li , Chao Shu , Long-Wu Ye , Qing Sun , Bo Zhou , Xin-Qi Zhu . Gold-catalyzed intermolecular amination of allyl azides with ynamides: Efficient construction of 3-azabicyclo[3.1.0] scaffold. Chinese Chemical Letters, 2025, 36(2): 109895-. doi: 10.1016/j.cclet.2024.109895
14. [14]
  Qianxi Wang , Xiaoqi Li , Fen Zhang , Qingyin Wei , Zengshan Yue , Xiantan Lin , Yicong Lv , Xitao Liu , Junhua Luo . Mixed cation ordering scaffold polar 2D halide perovskite semiconductor for self-powered polarization-sensitive photodetection. Chinese Chemical Letters, 2025, 36(10): 110405-. doi: 10.1016/j.cclet.2024.110405
15. [15]
  Yuexi Guo , Zhaoyang Li , Jingwei Dai . Charlie and the 3D Printing Chocolate Factory. University Chemistry, 2024, 39(9): 235-242. doi: 10.3866/PKU.DXHX202309067
16. [16]
  Qi Zhang , Bin Han , Yucheng Jin , Mingrun Li , Enhui Zhang , Jianzhuang Jiang . 2D and 3D phthalocyanine covalent organic frameworks for electrocatalytic carbon dioxide reduction. Chinese Chemical Letters, 2025, 36(9): 110330-. doi: 10.1016/j.cclet.2024.110330
17. [17]
  Lin Yang , Xia Liu , Bohan Li , Zhuo Liu , Yani Li , Canzhi Shi , Yan Xu . Emission regulation in 0D hybrid copper halides via structural transformation: From defect to non-defect states for information encryption and storage. Chinese Chemical Letters, 2026, 37(5): 110858-. doi: 10.1016/j.cclet.2025.110858
18. [18]
  Jie XIE , Hongnan XU , Jianfeng LIAO , Ruoyu CHEN , Lin SUN , Zhong JIN . Nitrogen-doped 3D graphene-carbon nanotube network for efficient lithium storage. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1840-1849. doi: 10.11862/CJIC.20240216
19. [19]
  Xi Xu , Chaokai Zhu , Leiqing Cao , Zhuozhao Wu , Cao Guan . Experiential Education and 3D-Printed Alloys: Innovative Exploration and Student Development. University Chemistry, 2024, 39(2): 347-357. doi: 10.3866/PKU.DXHX202308039
20. [20]
  Qiang Zhou , Pingping Zhu , Wei Shao , Wanqun Hu , Xuan Lei , Haiyang Yang . Innovative Experimental Teaching Design for 3D Printing High-Strength Hydrogel Experiments. University Chemistry, 2024, 39(6): 264-270. doi: 10.3866/PKU.DXHX202310064

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(2144)
HTML views(60)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142