Citation: Jianqiang Chen, Lingwei Wu, Jie Wu. Kojic acid and maltol: The "Transformers" in organic synthesis[J]. Chinese Chemical Letters, ;2020, 31(12): 2993-2995. doi: 10.1016/j.cclet.2020.06.034 shu

Kojic acid and maltol: The "Transformers" in organic synthesis

Jianqiang Chen ^a ,
Lingwei Wu ^a ,
Jie Wu ^{a, b, *,}

a.
School of Pharmaceutical and Materials Engineering & Institute for Advanced Studies, Taizhou University, Taizhou 318000, China
b.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

jie_wu@fudan.edu.cn

Received Date: 28 May 2020
Revised Date: 11 June 2020
Accepted Date: 24 June 2020
Available Online: 24 June 2020

Figures(5)

The deconstructive reorganization strategy for the synthesis of benzene-containing products from the kojic acid- and maltol-derived alkynes has been recently reported. In this strategy, kojic acid and maltol are analogous to the "Transformers", which can transform into benzofurans and benzaldehydes via annulation reactions. Under the synthetic standpoint, this deconstructive reorganization strategy features high atom economy, innate scalability and functional group tolerance. In the near future, we believe that this unique method will be widely investigated and other novel transformations of kojic acid and maltol will be discovered.
- Kojic acids,
- Maltols,
- Rearrangement,
- Deconstructive reorganization,
- Benzofurans
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