引用本文:
Jian Ta Wang, Ying Wang, Ji Quan Zhang, Xing Cui, Yi Zhang, Gao Feng Zhu, Lei Tang. Diclofenac derivatives with insulin-sensitizing activity[J]. Chinese Chemical Letters,
2011, 22(4): 409-412.
doi:
10.1016/j.cclet.2010.11.008
Citation: Jian Ta Wang, Ying Wang, Ji Quan Zhang, Xing Cui, Yi Zhang, Gao Feng Zhu, Lei Tang. Diclofenac derivatives with insulin-sensitizing activity[J]. Chinese Chemical Letters, 2011, 22(4): 409-412. doi: 10.1016/j.cclet.2010.11.008
Citation: Jian Ta Wang, Ying Wang, Ji Quan Zhang, Xing Cui, Yi Zhang, Gao Feng Zhu, Lei Tang. Diclofenac derivatives with insulin-sensitizing activity[J]. Chinese Chemical Letters, 2011, 22(4): 409-412. doi: 10.1016/j.cclet.2010.11.008
Diclofenac derivatives with insulin-sensitizing activity
摘要:
A series of diclofenac derivatives were synthesized. The insulin-sensitizing activity of 28 new compounds was evaluated in 3T3-L1 cells. The compounds 10a and 10f exhibited similar insulin-sensitizing activity with positive drag rosiglitazone.
English
Diclofenac derivatives with insulin-sensitizing activity
Abstract:
A series of diclofenac derivatives were synthesized. The insulin-sensitizing activity of 28 new compounds was evaluated in 3T3-L1 cells. The compounds 10a and 10f exhibited similar insulin-sensitizing activity with positive drag rosiglitazone.
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Key words:
- Diclofenac derivatives
- / Synthesis
- / Insulin-sensitizing activity
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