Citation: Chong Yao, Shu Jie Zhang, Zheng Zhong Bai, Tong Zhou, Li Jiang Xuan. Two new benzopyran derivatives from Gouania leptostachya DC.var.tonkinensis Pitard.[J]. Chinese Chemical Letters, ;2011, 22(2): 175-177. doi: 10.1016/j.cclet.2010.09.028 shu

Two new benzopyran derivatives from Gouania leptostachya DC.var.tonkinensis Pitard.

a Huzhou Central Hospital, Huzhou 313000, China;
b Heilongjiang University of Chinese Medicine, Harbin 150040, China;
c Heilongjiang Institute for Drug Control, Harbin 150001, China;
d State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai 201203, China

Received Date: 27 May 2010

Fund Project: The authors gratefully acknowledge grants from the National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program", China (No. 2009ZX09301-001).

Two new benzopyran derivatives, l-[(rel 25,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]ethanone (1), and l-[(rel 2S,35)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]ethanone (2), along with four known flavonoids, prodelphinidin C, pro-delphinidin B3, (-)-epi-gallocatechin and (+)-gallocatechin, were isolated from the stems of Gouania leptostachya DC. var. tonkinensis Pitard. Their structures were determined on the basis of spectroscopic methods including HR-ESI-MS, ID and 2D NMR. Prodelphinidin C exhibited significant inhibitory activity for α-glucosidase.
- Gouania leptostachya DC.var.tonkinensis Pitard.,
- Benzopyran derivatives,
- α-Glucosidase inhibitory activity
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