Citation: Yun Mei Bi, Xiao Ying Gong, Wen Zhao Wang, Li Yub, Min Qi Hu, Li Dong Shao. Synthesis and characterization of new biodegradable thermosensitive polyphosphazenes with lactic acid ester and methoxyethoxyethoxy side groups[J]. Chinese Chemical Letters, ;2010, 21(2): 237-241. doi: 10.1016/j.cclet.2009.10.003 shu

Synthesis and characterization of new biodegradable thermosensitive polyphosphazenes with lactic acid ester and methoxyethoxyethoxy side groups

a College of Chemistry and Engineering, Yunnan Normal University, Kunming 650092, China;
b College of Chemistry and Chemical Engineering, Chonqing College of Science and Technology, Chongqing 40042, China

Received Date: 10 June 2009

Fund Project: The authors gratefully acknowledge support for this work of the National Natural Foundation of China (No. 20364002) and the Natural Science Foundation of Yunnan Province (No. 2005B0027 M), China.

Two novel biodegradable thermosensitive polyphosphazenes with lactic acid ester and methoxyethoxyethoxy side groups were synthesized via the macromolecular substitution reactions of poly(dichlorophosphazene)with the sodium salt of lactic acid ester and sodium methoxyethoxyethoxide.Their structures were confirmed by ³¹p NMR,¹H NMR,¹³C NMR,IR,DSC,and elemental analysis.The lower critical solution temperature(LCST)behavior in water and in vitro degradation property of the polymers was investigated.The results indicated that two polymers showed LCST phase transition over a range of concentrations from 0.13 to 15 wt% and pH-sensitive degradation properties.
- Polyphosphazene,
- Lactic acid ester,
- Methoxyethoxyethoxy,
- Biodegradation,
- Thermosensitive polymer
1. [1]
  Husitu Lin , Shuangkun Zhang , Dianfa Zhao , Yongkang Wang , Wei Liu , Fan Yang , Jianjun Liu , Dongpeng Yan , Zhanpeng Wu . Flexible polyphosphazene nanocomposite films: Enhancing stability and luminescence of CsPbBr₃ perovskite nanocrystals. Chinese Chemical Letters, 2025, 36(4): 109795-. doi: 10.1016/j.cclet.2024.109795
2. [2]
  Xiangqian Cao , Chenkai Yang , Xiaodong Zhu , Mengxin Zhao , Yilin Yan , Zhengnan Huang , Jinming Cai , Jingming Zhuang , Shengzhou Li , Wei Li , Bing Shen . Synergistic enhancement of chemotherapy for bladder cancer by photothermal dual-sensitive nanosystem with gold nanoparticles and PNIPAM. Chinese Chemical Letters, 2024, 35(8): 109199-. doi: 10.1016/j.cclet.2023.109199
3. [3]
  Yiyang Zhang , Guangshu Yuan , Xiangkun Meng , Xu Zhang , Lei Yu . Promoting the catalytic activities of polyanilines for L-lactic acid condensation by calcium-doping: A biocompatible strategy. Chinese Chemical Letters, 2025, 36(12): 111069-. doi: 10.1016/j.cclet.2025.111069
4. [4]
  Xiaoman Dang , Zhiying Wu , Tangxin Xiao , Zhouyu Wang , Leyong Wang . Highly robust supramolecular polymer networks crosslinked by metallacycles. Chinese Chemical Letters, 2024, 35(12): 110208-. doi: 10.1016/j.cclet.2024.110208
5. [5]
  Yaohua Li , Qi Cao , Xuanhua Li . Tailoring the configuration of polymer passivators in perovskite solar cells. Chinese Journal of Structural Chemistry, 2025, 44(2): 100413-100413. doi: 10.1016/j.cjsc.2024.100413
6. [6]
  Chong Liu , Ling Li , Jiahui Gao , Yanwei Li , Nazhen Zhang , Jing Zang , Cong Liu , Zhaopei Guo , Yanhui Li , Huayu Tian . The study of antibacterial activity of cationic poly(β-amino ester) regulating by amphiphilic balance. Chinese Chemical Letters, 2025, 36(2): 110118-. doi: 10.1016/j.cclet.2024.110118
7. [7]
  Tiankai Sun , Hui Min , Zongsu Han , Liang Wang , Peng Cheng , Wei Shi . Rapid detection of nanoplastic particles by a luminescent Tb-based coordination polymer. Chinese Chemical Letters, 2024, 35(5): 108718-. doi: 10.1016/j.cclet.2023.108718
8. [8]
  Mengjun Sun , Zhi Wang , Jvhui Jiang , Xiaobing Wang , Chuang Yu . Gelation mechanisms of gel polymer electrolytes for zinc-based batteries. Chinese Chemical Letters, 2024, 35(5): 109393-. doi: 10.1016/j.cclet.2023.109393
9. [9]
  Huimin Gao , Zhuochen Yu , Xuze Zhang , Xiangkun Yu , Jiyuan Xing , Youliang Zhu , Hu-Jun Qian , Zhong-Yuan Lu . A mini review of the recent progress in coarse-grained simulation of polymer systems. Chinese Journal of Structural Chemistry, 2024, 43(5): 100266-100266. doi: 10.1016/j.cjsc.2024.100266
10. [10]
  Dong Lv , Xuelei Liu , Wei Li , Qiang Zhang , Xinhong Yu , Yanchun Han . Single droplet formation by controlling the viscoelasticity of polymer solutions during inkjet printing. Chinese Chemical Letters, 2024, 35(6): 109401-. doi: 10.1016/j.cclet.2023.109401
11. [11]
  Jinjie Lu , Qikai Liu , Yuting Zhang , Yi Zhou , Yanbo Zhou . Antibacterial performance of cationic quaternary phosphonium-modified chitosan polymer in water. Chinese Chemical Letters, 2024, 35(9): 109406-. doi: 10.1016/j.cclet.2023.109406
12. [12]
  Shaohua Zhang , Xiaojuan Dai , Wei Hao , Liyao Liu , Yingqiao Ma , Ye Zou , Jia Zhu , Chong-an Di . A first-principles study of the Nernst effect in doped polymer. Chinese Chemical Letters, 2024, 35(12): 109837-. doi: 10.1016/j.cclet.2024.109837
13. [13]
  Xu Li , Yue Zhao , Tingli Ma . Improved polymer electrolyte interfacial contact via constructing vertically aligned fillers. Chinese Journal of Structural Chemistry, 2025, 44(2): 100406-100406. doi: 10.1016/j.cjsc.2024.100406
14. [14]
  Xingjie Li , Chengjun Yi , Weifei Hu , Huishan Zhang , Jiale Xia , Yuanyuan Li , Jinping Liu . Emerging sulfide-polymer composite solid electrolyte membranes. Chinese Chemical Letters, 2025, 36(6): 110215-. doi: 10.1016/j.cclet.2024.110215
15. [15]
  Lei Zhang , Chenyang Kou , Kun Ni , Yiwen Chen , Tongchuan Zhang , Baoliang Zhang . Microenvironment regulation of copper sites by chelating hydrophobic polymer for electrosynthesis of ethylene. Chinese Chemical Letters, 2025, 36(6): 110836-. doi: 10.1016/j.cclet.2025.110836
16. [16]
  Xiaonan LI , Hui HAN , Yihan ZHANG , Jing XIONG , Tingting GUO , Juanzhi YAN . A viologen‐based Cd(Ⅱ) coordination polymer: Self‐assembly, thermochromism, and electrochemical property. Chinese Journal of Inorganic Chemistry, 2025, 41(7): 1439-1444. doi: 10.11862/CJIC.20240376
17. [17]
  Hongfei Li , Hao Chen , Qi Kang , Lihe Guo , Xingyi Huang , Haiping Xu . Gel polymer electrolyte for flexible and stretchable lithium metal battery: Advances and prospects. Chinese Chemical Letters, 2025, 36(9): 110325-. doi: 10.1016/j.cclet.2024.110325
18. [18]
  Weinan Hu , Li Li , Xinyu Wang , Yongqiang Zhang , Maoping Song , Linlin Shi , Xinqi Hao , Siyu Lu . Carbonized polymer dots: Illuminating synthesis pathways, optical frontiers, and photoelectronic breakthroughs. Chinese Chemical Letters, 2025, 36(11): 111612-. doi: 10.1016/j.cclet.2025.111612
19. [19]
  Gongxi Li , Jun Jin , Junxuan Tu , Haoguo Yue , Ying Wang , Xiaohui Jia , Weiyuan Yin , Zhenglin Han , Yuxuan Deng , Chunfeng Shi , Yonggang Zhen . Intrinsically stretchable polymer semiconductors synergistically constructed by hydrogen bonds and metal coordination. Chinese Chemical Letters, 2025, 36(12): 111716-. doi: 10.1016/j.cclet.2025.111716
20. [20]
  Jiabin Zhang , Xiaoke Zhang , Lilei Wang , Lingpeng Yan , Xueli Cheng , Tao Li . Fluorinated fused azobenzene boron-based polymer acceptors with 1000 nm absorbance edges for all-polymer solar cells. Chinese Chemical Letters, 2025, 36(7): 111064-. doi: 10.1016/j.cclet.2025.111064

Get Citation

PDF

XML

Metrics

PDF Downloads(1)
Abstract views(1138)
HTML views(41)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Address：Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888

DownLoad: Full-Size Img PowerPoint

Return