Citation: Hong Yun Guo Ji Chao Li, You Le Shang. A simple and efficient synthesis of 2-substituted benzothiazoles catalyzed by H₂O₂/HCl[J]. Chinese Chemical Letters, ;2009, 20(12): 1408-1410. doi: 10.1016/j.cclet.2009.06.037 shu

A simple and efficient synthesis of 2-substituted benzothiazoles catalyzed by H₂O₂/HCl

College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, China

Received Date: 20 April 2009

Fund Project: We are thankful Education Department of Zhejiang Province (No.20060811) for the financial support of this work.

A simple and efficient procedure for the synthesis of substituted benzothiazoles through condensation of 2-aminothiophenol with aromatic aldehydes in the presence of H ₂O₂/HCl system in ethanol at room temperature is described.The target compounds have been characterized by ¹H NMR,¹³C NMR, IR and MS.Short reaction time, easy and quick isolation of the products, and excellent yields are the main advantages of this procedure.
- 2-Substituted benzothiazoles,
- Heterocyclic compounds,
- H₂O₂/HCl
1. [1]
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2. [2]
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3. [3]
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6. [6]
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7. [7]
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8. [8]
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9. [9]
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10. [10]
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12. [12]
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13. [13]
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14. [14]
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15. [15]
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16. [16]
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17. [17]
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18. [18]
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19. [19]
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20. [20]
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