Synthesis of a hypocrellin B-polyamide conjugate as DNA-targeting photosensitizer

Yan Yan Liu Sheng Qin Xia Zhang Hua Zeng Rui Qiao Xue Song Wang Bao Wen Zhang

引用本文: Yan Yan Liu,  Sheng Qin Xia,  Zhang Hua Zeng,  Rui Qiao,  Xue Song Wang,  Bao Wen Zhang. Synthesis of a hypocrellin B-polyamide conjugate as DNA-targeting photosensitizer[J]. Chinese Chemical Letters, 2008, 19(2): 157-160. doi: 10.1016/j.cclet.2007.11.013 shu
Citation:  Yan Yan Liu,  Sheng Qin Xia,  Zhang Hua Zeng,  Rui Qiao,  Xue Song Wang,  Bao Wen Zhang. Synthesis of a hypocrellin B-polyamide conjugate as DNA-targeting photosensitizer[J]. Chinese Chemical Letters, 2008, 19(2): 157-160. doi: 10.1016/j.cclet.2007.11.013 shu

Synthesis of a hypocrellin B-polyamide conjugate as DNA-targeting photosensitizer

  • 基金项目:

    This work was financially supported by NNSFC (No. 20772133) and the Chinese Academy of Sciences (No. KJCX2.YW.H08).

摘要: A new hypocrellin B (HB) derivative bearing a bispyrrolecarboxamide-containing side chain was synthesized, which presents improved absorptivity in phototherapeutic window than Hb and affinity feature towards dsDNA.

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  • 收稿日期:  2007-09-26
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