Citation: Xiaoshan Yan, Xiaotong Yang, Xinming Tong, Yanbin Huang. A Method to Accelerate the Gelation of Disulfide-crosslinked Hydrogels[J]. Chinese Journal of Polymer Science, ;2015, 33(1): 118-127. doi: 10.1007/s10118-015-1567-5 shu

A Method to Accelerate the Gelation of Disulfide-crosslinked Hydrogels

1.
Key Laboratory of Advanced Materials (MOE), Department of Chemical Engineering, Tsinghua University, Beijing 100084, China

Received Date: 25 April 2014
Revised Date: 31 May 2014

Fund Project: This work was financially supported by the National Natural Science Foundation of China (No. 21004038).

A glutathione-disulfide-ended poly(ethylene glycol) (GSSG-PEG-GSSG) was designed. It is a much more efficient accelerator than glutathione disulfide (GSSG) for the gelation of an 8arm-PEG-SH polymer solution, and the gelation time can be tuned from hours to minutes at the physiological pH and temperature. A mechanism was proposed to explain the different behaviors of the GSSG and GSSG-PEG-GSSG gelation systems. Due to the ever-going thiol-disulfide exchange reaction, the thiol-disulfide hydrogels also showed interesting swelling behavior.
- Thiol-disulfide exchange,
- In situ gelation,
- Glutathione,
- PEG
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
11. [11]
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
20. [20]
21. [21]
22. [22]
23. [23]
24. [24]
1. [1]
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