Citation: Yang-ping Wen, Dong Li, Yao Lu, Hao-hua He, Jing-kun Xu, Xue-min Duan, Ming Liu. POLY(3,4-ETHYLENEDIOXYTHIOPHENE METHANOL)/ASCORBATE OXIDASE/NAFION-SINGLE-WALLED CARBON NANOTUBES BIOSENSOR FOR VOLTAMMETRIC DETECTION OF VITAMIN C[J]. Chinese Journal of Polymer Science, ;2012, 30(3): 460-469. doi: 10.1007/s10118-012-1140-4 shu

POLY(3,4-ETHYLENEDIOXYTHIOPHENE METHANOL)/ASCORBATE OXIDASE/NAFION-SINGLE-WALLED CARBON NANOTUBES BIOSENSOR FOR VOLTAMMETRIC DETECTION OF VITAMIN C

Received Date: 1 August 2011
Revised Date: 17 October 2011

Fund Project: This work was financially supported by NSFC (Nos. 50963002, 51073074), Key Projects in the National Science Technology Pillar Program in the Eleventh Five-year Plan Period (Nos. 2006BAD02A04, 2006BAD01A01), Jiangxi Provincial Department of Science and Technology (No. 2006BAD01A01-2-5), Jiangxi Provincial Department of Education (Nos. GJJ11590, GJJ10678), Natural Science Foundation of Jiangxi Province (No. 2010GZH0041), Key Laboratory of Photochemical Conversion and Optoelectronic Materials, TIPC, CAS, and Jiangxi Provincial Innovation Fund of Postgraduates (No. YC10A063).

Vitamin C (VC) content in commercial juices was voltammetrically determined using a highly selective and sensitive poly(3,4-ethylenedioxythiophene methanol)/ascorbate oxidase/Nafion-single-walled carbon nanotubes (PEDOTM/AO/Nafion-SWCNT) biosensor. The biocompatible PEDOTM matrix was prepared facilely by the one-step electrochemical deposition technique in lithium perchlorate aqueous solutions. AO was dip-coated on the surface of the biocompatible PEDOTM matrix. The mixture of Nafion-SWCNT was dip-cast onto the surface of AO layer when it was obtained by blending Nafion solution and SWCNT dispersion together in a volume ratio of 1:1. The prepared PEDOTM/AO/Nafion-SWCNT biosensor was used for the voltammetric determination of VC, which exhibited the good linear range (4.0 ? 10-5-3 ? 10-3 mol/L), low detection limit (13 祄ol/L), pronounced sensitivity (1.4072 mA (mmol/L)-1 cm-2), high bioaffinity (low apparent Michaelis-Menten constant), good stability (good repeatability), high specificity (good anti-interference ability) coupled with the good reliability and feasibility (the determination of VC in commercial juices). Meanwhile, the good aqueous solubility and the low onset oxidation potential of EDOTM will be more beneficial to the application in biosensor field compared to 3,4-ethylenedioxythiophene. Moreover, the good biocompatibility of PEDOTM matrix and high selectivity of Nafion-SWCNT films also provide a promising platform for the development of biosensing devices.
- Biosensor
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