Study on the Interaction of Pd-TMPyP with ctDNA by Solid-substrate Room Temperature Phosphorescence

Li Min GUO Wen Juan DONG Chuan DONG

引用本文: Li Min GUO,  Wen Juan DONG,  Chuan DONG. Study on the Interaction of Pd-TMPyP with ctDNA by Solid-substrate Room Temperature Phosphorescence[J]. Chinese Chemical Letters, 2006, 17(2): 253-254. shu
Citation:  Li Min GUO,  Wen Juan DONG,  Chuan DONG. Study on the Interaction of Pd-TMPyP with ctDNA by Solid-substrate Room Temperature Phosphorescence[J]. Chinese Chemical Letters, 2006, 17(2): 253-254. shu

Study on the Interaction of Pd-TMPyP with ctDNA by Solid-substrate Room Temperature Phosphorescence

  • 基金项目:

    This work was supported by the National Natural Science Foundation of China (No.20275022).

摘要: The interaction between calf thymus DNA (ctDNA) and Pd (Ⅱ) meso-tetrakis(4-N-methyl pyridiniumyl) porphyrin (Pd-TMPyP) was investigated by steady solid-substrate room temperature phosphorescence (SS-RTP). The SS-RTP intensity and lifetime of Pd-TMPyP enhanced with the increasing ctDNA. The anion quenching experiment of Pd-TMPyP indicated that Pd-TMPyP intercalated into ctDNA, which was also approved by UV-Vis spectra.

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  • 收稿日期:  2005-06-22
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