A Facile Synthesis of N-Phosphoryl Amino Acids Containing Hydroxy Group

Jian Chen ZHANG Shu Xia CAO Xiao Li YANG Yu Fen ZHAO

引用本文: Jian Chen ZHANG,  Shu Xia CAO,  Xiao Li YANG,  Yu Fen ZHAO. A Facile Synthesis of N-Phosphoryl Amino Acids Containing Hydroxy Group[J]. Chinese Chemical Letters, 2004, 15(6): 646-648. shu
Citation:  Jian Chen ZHANG,  Shu Xia CAO,  Xiao Li YANG,  Yu Fen ZHAO. A Facile Synthesis of N-Phosphoryl Amino Acids Containing Hydroxy Group[J]. Chinese Chemical Letters, 2004, 15(6): 646-648. shu

A Facile Synthesis of N-Phosphoryl Amino Acids Containing Hydroxy Group

  • 基金项目:

    We thank the financial supports from the National Natural Science Foundation of China (No.20132020), The Ministry of Science and Technology, The Chinese Ministry of Education and Zhengzhou University.

摘要: three kinds of N-(diisopropyloxyphosphoryl) amino acids containing hydroxyl group were prepared in high yield by using diisopropyl phosphite as the phosphorylating agent, sodium hypochlorite as the chlorinating agent and tetrabutyl ammonium bromide as the phase transfer catalyst in basic aqueous media.

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  • 收稿日期:  2003-06-17
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