引用本文:
Zi Li XIAO, Ren WEN, An Gou MO, Xi Peng JING, Feng Yan SUN. 1-SUBSTITUTED PHENYL-β-CARBOLINES:SYNTHESIS AND SPECIFIC BINDING WITH BENZODIAZEPINE RECEPTOR[J]. Chinese Chemical Letters,
1991, 3(9): 677-680.
Citation: Zi Li XIAO, Ren WEN, An Gou MO, Xi Peng JING, Feng Yan SUN. 1-SUBSTITUTED PHENYL-β-CARBOLINES:SYNTHESIS AND SPECIFIC BINDING WITH BENZODIAZEPINE RECEPTOR[J]. Chinese Chemical Letters, 1991, 3(9): 677-680.
Citation: Zi Li XIAO, Ren WEN, An Gou MO, Xi Peng JING, Feng Yan SUN. 1-SUBSTITUTED PHENYL-β-CARBOLINES:SYNTHESIS AND SPECIFIC BINDING WITH BENZODIAZEPINE RECEPTOR[J]. Chinese Chemical Letters, 1991, 3(9): 677-680.
1-SUBSTITUTED PHENYL-β-CARBOLINES:SYNTHESIS AND SPECIFIC BINDING WITH BENZODIAZEPINE RECEPTOR
摘要:
By the condensation of tryptamine with appropriate substituted benzaldehyde followed by Pictet-Spengler reaction, a series of 1-aryl-tetrahydro-β-carbo-lines(THβCs)were obtained.After dehydrogenation using sulfur, Pd-C or lead tetraacetate(LTA), these THβCs can give the corresponding β-carbolines(βCs)which exhibit specific binding with rat brain benzodiazepine receptor in vitro.
English
1-SUBSTITUTED PHENYL-β-CARBOLINES:SYNTHESIS AND SPECIFIC BINDING WITH BENZODIAZEPINE RECEPTOR
Abstract:
By the condensation of tryptamine with appropriate substituted benzaldehyde followed by Pictet-Spengler reaction, a series of 1-aryl-tetrahydro-β-carbo-lines(THβCs)were obtained.After dehydrogenation using sulfur, Pd-C or lead tetraacetate(LTA), these THβCs can give the corresponding β-carbolines(βCs)which exhibit specific binding with rat brain benzodiazepine receptor in vitro.
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