引用本文:
Shao Ning WANG, Ying Kun QIU, Hui XU, Yi Hui DENG, Da Wei CHEN. Synthesis and Characterization of a Novel Galactosylated Cholesterol[J]. Chinese Chemical Letters,
2006, 17(2): 173-176.
Citation: Shao Ning WANG, Ying Kun QIU, Hui XU, Yi Hui DENG, Da Wei CHEN. Synthesis and Characterization of a Novel Galactosylated Cholesterol[J]. Chinese Chemical Letters, 2006, 17(2): 173-176.
Citation: Shao Ning WANG, Ying Kun QIU, Hui XU, Yi Hui DENG, Da Wei CHEN. Synthesis and Characterization of a Novel Galactosylated Cholesterol[J]. Chinese Chemical Letters, 2006, 17(2): 173-176.
Synthesis and Characterization of a Novel Galactosylated Cholesterol
摘要:
A novel galactosylated cholesterol with mono-galactoside moiety, (5-cholesten-3-yl)4-oxo-4-[2-(lactobionylamido)ethylamido]butanoate 6 was synthesized. Its chemical structure was characterized by IR, ESI-MS, 13C NMR, 1H NMR. Doxorubicin entrapped in the liposomes containing 10% mol/mol 6 was rapidly accumulated in liver and mainly uptake by parenchymal cells in mice.
English
Synthesis and Characterization of a Novel Galactosylated Cholesterol
Abstract:
A novel galactosylated cholesterol with mono-galactoside moiety, (5-cholesten-3-yl)4-oxo-4-[2-(lactobionylamido)ethylamido]butanoate 6 was synthesized. Its chemical structure was characterized by IR, ESI-MS, 13C NMR, 1H NMR. Doxorubicin entrapped in the liposomes containing 10% mol/mol 6 was rapidly accumulated in liver and mainly uptake by parenchymal cells in mice.
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