SBA-15 Modified Carbon Paste Electrode for Rapid cTnI Detection with Enhanced Sensitivity

Nong Yue HE Hui Shi GUO Di YANG Chun Rong GU Ji Nan ZHANG

引用本文: Nong Yue HE,  Hui Shi GUO,  Di YANG,  Chun Rong GU,  Ji Nan ZHANG. SBA-15 Modified Carbon Paste Electrode for Rapid cTnI Detection with Enhanced Sensitivity[J]. Chinese Chemical Letters, 2006, 17(2): 235-238. shu
Citation:  Nong Yue HE,  Hui Shi GUO,  Di YANG,  Chun Rong GU,  Ji Nan ZHANG. SBA-15 Modified Carbon Paste Electrode for Rapid cTnI Detection with Enhanced Sensitivity[J]. Chinese Chemical Letters, 2006, 17(2): 235-238. shu

SBA-15 Modified Carbon Paste Electrode for Rapid cTnI Detection with Enhanced Sensitivity

  • 基金项目:

    This work was financially supported by NNSFC (60571032, 90406016), the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry of China, and the Trans-Century Training Programme Foundation for the Talents by the Ministry of Education of China.

摘要: A novel electrochemical immunoassay for cardiac troponin I (cTnI) combining the concepts of the dual monoclonal antibody "sandwich" principle, the silver enhancement on the nano-gold particle, and the SBA-15 mesoporous modified carbon paste electrode (SBA-MCPE) is described. Four main steps were carried out to obtain the analytical signal, i.e., electrode preparation, immunoreaction, silver enhancement, and anodic stripping voltammetric detection.A linear relationship between the anodic stripping peak current and concentration of cTnI from 0.5 to 5.0 ng/mL and a limit of detection of 0.2 ng/mL of cTnI were obtained.

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  • 收稿日期:  2005-07-07
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