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Silica-bonded N-propyl sulfamic acid as an efficient recyclable catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones under heterogeneous conditions

Srinivasa Rao Jetti ,  Anjna Bhatewara ,  Tanuja Kadre ,  Shubha Jain

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Citation:  Srinivasa Rao Jetti, Anjna Bhatewara, Tanuja Kadre, Shubha Jain. Silica-bonded N-propyl sulfamic acid as an efficient recyclable catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones under heterogeneous conditions[J]. Chinese Chemical Letters, 2014, 25(3): 469-473. doi: 10.1016/j.cclet.2013.12.022 shu

Silica-bonded N-propyl sulfamic acid as an efficient recyclable catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones under heterogeneous conditions

    • 通讯作者: Srinivasa Rao Jetti,
摘要: Silica-bonded N-propyl sulfamic acid (SBNPSA) catalyzed one-pot three component Biginelli condensation of different substituted aromatic aldehydes with ethyl acetoacetate and urea/thoiurea to the respective 3,4-dihydropyrimidin-2-(1H)-ones and thiones in environment friendly procedure is described. The facile reaction conditions, simple isolation and purification procedures of this method make it a good option for the synthesis of dihydropyrimidinones.

English

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  • 发布日期:  2013-12-24
  • 收稿日期:  2013-10-14
  • 网络出版日期:  2013-12-05
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