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A practical synthesis of bis(indolyl)methanes catalyzed by BF3·Et2O

Xia-Fei Xu ,  Yan Xiong ,  Xue-Ge Ling ,  Xi-Mi Xie ,  Jie Yuan ,  Shu-Ting Zhang ,  Zhong-Rong Song

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Citation:  Xia-Fei Xu, Yan Xiong, Xue-Ge Ling, Xi-Mi Xie, Jie Yuan, Shu-Ting Zhang, Zhong-Rong Song. A practical synthesis of bis(indolyl)methanes catalyzed by BF3·Et2O[J]. Chinese Chemical Letters, 2014, 25(3): 406-410. doi: 10.1016/j.cclet.2013.11.038 shu

A practical synthesis of bis(indolyl)methanes catalyzed by BF3·Et2O

    • 通讯作者: Yan Xiong,
    Zhong-Rong Song,
  • 基金项目:

    We are grateful for scientific research fundings from the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry, Partenariats Hubert Curien Xu Guangqi 2012 (No. 27967RE) (No. 27967RE)

摘要: Practical BF3·Et2O catalyzed reactions between indoles and a series of carbonyl compounds at room temperature are described, which afford bis(indolyl)methanes with isolated yields up to 96%.

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    33. [33] The crystal data of compound 3j (CCDC reference number 946729): C27H20N2, M = 372.46, crystal system: monoclinic, space group: P21/c, lattice parameters: a = 10.722(6)Å, b = 15.124(6)Å, c = 15.355(9)Å, α = 90°, β = 105.159(11)°, γ = 90°, V = 2406(2)Å3, Z = 4, Dc = 1.244 g/cm-3, F000 = 952, final R indices[I > 2sigma(I)]: R1 = 0.0670, wR2 = 0.2023.[33] The crystal data of compound 3j (CCDC reference number 946729): C27H20N2, M = 372.46, crystal system: monoclinic, space group: P21/c, lattice parameters: a = 10.722(6)Å, b = 15.124(6)Å, c = 15.355(9)Å, α = 90°, β = 105.159(11)°, γ = 90°, V = 2406(2)Å3, Z = 4, Dc = 1.244 g/cm-3, F000 = 952, final R indices[I > 2sigma(I)]: R1 = 0.0670, wR2 = 0.2023.

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  • 发布日期:  2013-11-28
  • 收稿日期:  2013-08-19
  • 网络出版日期:  2013-11-11
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