引用本文:
Min Wang, Ting Ting Zhang, Zhi Guo Song. Eco-friendly synthesis of 2-substituted-2,3-dihydro-4(1H)-quinazolinones in water[J]. Chinese Chemical Letters,
2011, 22(4): 427-430.
doi:
10.1016/j.cclet.2010.10.038
Citation: Min Wang, Ting Ting Zhang, Zhi Guo Song. Eco-friendly synthesis of 2-substituted-2,3-dihydro-4(1H)-quinazolinones in water[J]. Chinese Chemical Letters, 2011, 22(4): 427-430. doi: 10.1016/j.cclet.2010.10.038
Citation: Min Wang, Ting Ting Zhang, Zhi Guo Song. Eco-friendly synthesis of 2-substituted-2,3-dihydro-4(1H)-quinazolinones in water[J]. Chinese Chemical Letters, 2011, 22(4): 427-430. doi: 10.1016/j.cclet.2010.10.038
Eco-friendly synthesis of 2-substituted-2,3-dihydro-4(1H)-quinazolinones in water
摘要:
2-Substituted-2,3-dihydro-4(1H)-quinazolinones were synthesized in high yield by condensation of 2-anthranilamide with aromatic aldehydes or ketones in refluxing water without catalyst. This protocol has advantages of high yield, simple work-up and environmental friendly procedure.
English
Eco-friendly synthesis of 2-substituted-2,3-dihydro-4(1H)-quinazolinones in water
Abstract:
2-Substituted-2,3-dihydro-4(1H)-quinazolinones were synthesized in high yield by condensation of 2-anthranilamide with aromatic aldehydes or ketones in refluxing water without catalyst. This protocol has advantages of high yield, simple work-up and environmental friendly procedure.
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Key words:
- 2,3-Dihydro-4(1H)-quinazolinone
- / 2-Anthranilamide
- / Aldehydes
- / Ketones
- / Synthesis in water
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