Evaluation of lipid peroxidation inhibition and free radical scavenging abilities of 5,6,7-trimethoxy dihydroflavonols

Ke Xin Huang Yu Bing Feng Wei Yao Lei Xiang Yang Feng Wang Hai Bo Li Su Zeng Jing Xu Gong Ming Hui Hu Yu Zhao Xiu Mei Wu Xiao Kun Li Jia Qu

引用本文: Ke Xin Huang,  Yu Bing Feng,  Wei Yao,  Lei Xiang Yang,  Feng Wang,  Hai Bo Li,  Su Zeng,  Jing Xu Gong,  Ming Hui Hu,  Yu Zhao,  Xiu Mei Wu,  Xiao Kun Li,  Jia Qu. Evaluation of lipid peroxidation inhibition and free radical scavenging abilities of 5,6,7-trimethoxy dihydroflavonols[J]. Chinese Chemical Letters, 2009, 20(10): 1187-1190. doi: 10.1016/j.cclet.2009.04.026 shu
Citation:  Ke Xin Huang,  Yu Bing Feng,  Wei Yao,  Lei Xiang Yang,  Feng Wang,  Hai Bo Li,  Su Zeng,  Jing Xu Gong,  Ming Hui Hu,  Yu Zhao,  Xiu Mei Wu,  Xiao Kun Li,  Jia Qu. Evaluation of lipid peroxidation inhibition and free radical scavenging abilities of 5,6,7-trimethoxy dihydroflavonols[J]. Chinese Chemical Letters, 2009, 20(10): 1187-1190. doi: 10.1016/j.cclet.2009.04.026 shu

Evaluation of lipid peroxidation inhibition and free radical scavenging abilities of 5,6,7-trimethoxy dihydroflavonols

摘要: Four naturally rare 5,6,7-trimethoxy-2,3-cis-dihydroflavonols (3-6) and two 5,6,7-trimethoxy-2,3-trans-dihydroflavonols (7-8)were designed and synthesized.Their antioxidative properties were evaluated by way of examining their scavenging capacities towards DPPH and O2·-.free radicals, as well as by measuring their inhibitory ability against LPO.Both the 2,3-trans and the 2,3-cis conformers exhibited certain quenching abilities to DPPH and O2·- radicals, while most of the synthetic dihydroflavonols demonstrated remarkable inhibition to LPO.

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  • 收稿日期:  2009-03-02
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